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1

Enhanced glutathione PEGylated liposomal brain delivery of an anti-amyloid single domain antibody fragment in a mouse model for Alzheimer's disease

Rotman, Maarten, Welling, Mick M., Bunschoten, Anton, de Backer, Maaike E., Rip, Jaap, Nabuurs, Rob J.A., Gaillard, Pieter J., van Buchem, Mark A., van der Maarel, Silvère M., van der Weerd, Louise

Journal:

Journal of Controlled Release

Year:

2015

Language:

english

File:

PDF, 1.93 MB

english, 2015

2

Enhanced Brain Delivery of the Opioid Peptide DAMGO in Glutathione PEGylated Liposomes: A Microdialysis Study

Lindqvist, Annika, Rip, Jaap, Gaillard, Pieter J, Björkman, Sven, Hammarlund-Udenaes, Margareta

Journal:

Molecular Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 1.19 MB

english, 2013

3

Societal embedding and product creation management

Jasper Deuten, J., Rip, Arie, Jelsma, Jaap

Journal:

Technology Analysis & Strategic Management

Year:

1997

Language:

english

File:

PDF, 943 KB

english, 1997

4

Enhanced brain delivery of liposomal methylprednisolone improved therapeutic efficacy in a model of neuroinflammation

Gaillard, Pieter J., Appeldoorn, Chantal C.M., Rip, Jaap, Dorland, Rick, van der Pol, Susanne M.A., Kooij, Gijs, de Vries, Helga E., Reijerkerk, Arie

Journal:

Journal of Controlled Release

Year:

2012

Language:

english

File:

PDF, 618 KB

english, 2012

5

Long-Term Correction of Murine Lipoprotein Lipase Deficiency with AAV1-Mediated Gene Transfer of the Naturally Occurring LPL S447X Beneficial Mutation

Ross, Colin J.D., Twisk, Jaap, Meulenberg, Janneke M., Liu, Guoqing, Van Den Oever, Karin, Moraal, Ewoud, Hermens, Wim T., Rip, Jaap, Kastelein, John J.P., Kuivenhoven, Jan Albert, Hayden, Michael R.

Journal:

Human Gene Therapy

Year:

2004

Language:

english

File:

PDF, 6.14 MB

english, 2004

6

Glutathione conjugation dose-dependently increases brain-specific liposomal drug delivery in vitro and in vivo

Maussang, David, Rip, Jaap, van Kregten, Joan, van den Heuvel, Angelique, van der Pol, Susanne, van der Boom, Burt, Reijerkerk, Arie, Chen, Linda, de Boer, Marco, Gaillard, Pieter, de Vries, Helga

Journal:

Drug Discovery Today: Technologies

Year:

2016

Language:

english

File:

PDF, 1.21 MB

english, 2016

7

Targeted Blood-to-Brain Drug Delivery – 10 Key Development Criteria

J. Gaillard, Pieter, C. Visser, Corine, C.M. Appeldoorn, Chantal, Rip, Jaap

Journal:

Current Pharmaceutical Biotechnology

Year:

2012

Language:

english

File:

PDF, 379 KB

english, 2012

8

Efficient CRM197-mediated drug targeting to monocytes

Geert J. Schenk, P.C. Joost Haasnoot, Mireille Centlivre, Nicolas Legrand, Jaap Rip, Albertus G. de Boer, Ben Berkhout

Journal:

Journal of Controlled Release

Year:

2012

Language:

english

File:

PDF, 922 KB

english, 2012

9

Enhanced brain drug delivery: safely crossing the blood–brain barrier

Pieter J. Gaillard, Corine C. Visser, Chantal C.M. Appeldoorn, Jaap Rip

Journal:

Drug Discovery Today: Technologies

Year:

2012

Language:

english

File:

PDF, 124 KB

english, 2012

10

Systemic Treatment With Glutathione PEGylated Liposomal Methylprednisolone (2B3-201) Improves Therapeutic Efficacy in a Model of Ocular Inflammation

Reijerkerk, Arie, Appeldoorn, Chantal C. M., Rip, Jaap, de Boer, Marco, Gaillard, Pieter J.

Journal:

Investigative Opthalmology & Visual Science

Year:

2014

Language:

english

File:

PDF, 954 KB

english, 2014

11

Liposome technologies and drug delivery to the CNS

Journal:

Drug Discovery Today: Technologies

Year:

2016

Language:

english

File:

PDF, 452 KB

english, 2016

12

Glutathione PEGylated liposomes: pharmacokinetics and delivery of cargo across the blood–brain barrier in rats

Rip, Jaap, Chen, Linda, Hartman, Robin, van den Heuvel, Angelique, Reijerkerk, Arie, van Kregten, Joan, van der Boom, Burt, Appeldoorn, Chantal, de Boer, Marco, Maussang, David, de Lange, Elizabeth C.

Journal:

Journal of Drug Targeting

Year:

2014

Language:

english

File:

PDF, 436 KB

english, 2014

13

First evidence of efficacy in brain following intravenous injections of Brain-Targeted Liposome-Enzyme in the MPS II mouse model

Maurizio Scarpa, Eva Zaccariotto, Francesca D'Avanzo, Willem van Weperen, Jaap Rip, Pieter Gaillard, Rosella Tomanin

Journal:

Molecular Genetics and Metabolism

Year:

2011

Language:

english

File:

PDF, 57 KB

english, 2011

14

Carriers of the frequent lipoprotein lipase S447X variant exhibit enhanced postprandial apoprotein B-48 clearance

Melchior C. Nierman, Jaap Rip, Jan-Albert Kuivenhoven, Daniel H. van Raalte, Barbara A. Hutten, Naohiko Sakai, John J.P. Kastelein, Erik S.G. Stroes

Journal:

Year:

2005

Language:

english

File:

PDF, 140 KB

english, 2005

15

In vivoFunctional Evaluation of Increased Brain Delivery of the Opioid Peptide DAMGO by Glutathione-PEGylated Liposomes

Lindqvist, Annika, Rip, Jaap, van Kregten, Joan, Gaillard, Pieter J, Hammarlund-Udenaes, Margareta

Journal:

Pharmaceutical Research

Year:

2016

Language:

english

File:

PDF, 434 KB

english, 2016

16

In Vivo Quantitative Understanding of PEGylated Liposome’s Influence on Brain Delivery of Diphenhydramine

Hu, Yang, Gaillard, Pieter J, Rip, Jaap, de Lange, Elizabeth CM, Hammarlund-Udenaes, Margareta

Journal:

Molecular Pharmaceutics

Year:

2018

Language:

english

File:

PDF, 1.19 MB

english, 2018

17

Correction of Feline Lipoprotein Lipase Deficiency with Adeno-Associated Virus Serotype 1-Mediated Gene Transfer of the Lipoprotein Lipase S447X Beneficial Mutation

Ross, Colin J.D., Twisk, Jaap, Bakker, Andrew C., Miao, Fudan, Verbart, Dennis, Rip, Jaap, Godbey, Tamara, Dijkhuizen, Paul, Hermens, Wim T.J.M.C., Kastelein, John J.P., Kuivenhoven, Jan Albert, Meule

Journal:

Human Gene Therapy

Year:

2006

Language:

english

File:

PDF, 707 KB

english, 2006

18

AAV1-LPLS447X gene therapy reduces hypertriglyceridemia in apoE2 knock in mice

Jaap Rip, Ko Willems van Dijk, Jeroen A. Sierts, John J.P. Kastelein, Jaap Twisk, Jan Albert Kuivenhoven

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2006

Language:

english

File:

PDF, 256 KB

english, 2006

19

Adeno-associated virus LPLS447X gene therapy in LDL receptor knockout mice

Jaap Rip, Jeroen A. Sierts, Stefan F.C. Vaessen, John J.P. Kastelein, Jaap Twisk, Jan Albert Kuivenhoven

Journal:

Atherosclerosis

Year:

2007

Language:

english

File:

PDF, 289 KB

english, 2007

20

Drug targeting to the brain

Rip, Jaap, Schenk, Geert J, de Boer, Albertus G

Journal:

BMC Proceedings

Year:

2008

Language:

english

File:

PDF, 148 KB

english, 2008

21

The Impact of Liposomal Formulations on the Release and Brain Delivery of Methotrexate: An In Vivo Microdialysis Study

Hu, Yang, Rip, Jaap, Gaillard, Pieter J., de Lange, Elizabeth C.M., Hammarlund-Udenaes, Margareta

Journal:

Journal of Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 1.34 MB

english, 2017

22

Gene Therapy for Lipoprotein Lipase Deficiency: Working Toward Clinical Application

Rip, Jaap, Nierman, Melchior C., Sierts, Jeroen A., Petersen, Wilma, Den Oever, Karin Van, Raalte, Daniel Van, Ross, Colin J.D., Hayden, Michael R., Bakker, Andrew C., Dijkhuizen, Paul, Hermens, Wim T

Journal:

Human Gene Therapy

Year:

2005

Language:

english

File:

PDF, 189 KB

english, 2005

23

Enhanced apoB48 metabolism in lipoprotein lipase X447 homozygotes

Melchior C. Nierman, Jaap Rip, Jan Albert Kuivenhoven, Naohiko Sakai, John J.P. Kastelein, Monique G.M. de Sain-van der Velden, Erik S.G. Stroes, Berthil H.C.M.T. Prinsen

Journal:

Atherosclerosis

Year:

2007

Language:

english

File:

PDF, 165 KB

english, 2007

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